MAR™ and MAR™ Advantages
The MAR™ (Magnetic Assay Reader) is an innovative, patented technology platform capable of performing a wide range of biochemical assays with quantitative results via the detection of super paramagnetic particles (used as reporters) that are bound to the analyte of interest.

Compared to other particle-based assays, the use of super paramagnetic particles as reporter elements offers unique characteristics.

Advantages of MAR™ using magnetic particles as reporters in assays:

• High Sensitivity

The total amount of analyte is measured in one volumetric measurement. Therefore, the entire analyte contained within the detector’s active region will be measured, thereby contributing to sensitivity. This contrasts with the optical-sensing techniques in which only reporter-analyte interactions on a surface are detectable.

Side-by-side comparisons to visual lateral flow assays demonstrate a 10-1000 times increase in sensitivity.

• Quantitative Results

The MAR™ platform provides quantitative results by employing super paramagnetic particles as reporter elements. The amount of magnetization as determined by the MAR™ can be directly correlated to the amount of analyte in the sample.

• Linearity and Accuracy

The strength of magnetic signal increases directly with the mass of the magnetic label. MAR™ measurements have been demonstrated to be linear over a range of at least 4 orders of magnitude. This inherent linearity contributes to sensitivity, accuracy, and wide dynamic range.

• Rapid time-to-results

Measurement of each analytical region is performed in 9-15 seconds.

• Stable reagent and stable signal

Super paramagnetic particles are magnetic only when in a magnetic field. This allows them to be freely manipulated in solution without aggregating.

Super paramagnetic particles are stable, yielding reproducible measurement after an extended period of time. This property makes them ideal for archiving.

• Standard Conjugation Chemistry

Super paramagnetic particles are easily substituted for colloidal gold or latex particles. They can be adapted to a wide range of lateral flow assays. Other assay components such as membranes, sample and wicking pads, as well as production equipments, may remain relatively unchanged.